m6A (N6-methyladenosine) is the most common post-transcriptional modification of eukaryotic mRNAs, accounting for 80% of RNA methylation modifications. As early as the 1970s, m6A modifications have been identified in eukaryotic mRNA and lncRNA. The m6A genes consist of three groups, including writers, readers (IYT521-B homolog [YTH]) and erasers (alkylation repair protein-B [AlkB]).
  The erasers we were identified by going through 'PF13532' number and a total of 56 functional genes were obtained.AlkB belongs to the N6-methyladenosine erasers. the AlkB family of demethylases AlkB, FTO and ALKBH5 recognize different methylated RNA/DNA substrates. Among them, ALKBH5 is the m6A demethylase. The demethylases FTO and ALKBH5 recognize different methylated RNA/DNA substrates, respectively. Click here to download the full Erasers genes list.